AI-Driven Automation

2

Human Touches

in a 12-stage fully automated PA pipeline

NexusLedge automates the entire PA lifecycle from document intake to determination letters. Only clinical review and final determination require human judgment.

End-to-End Pipeline

12 stages. 10 automated. 2 human.

1

Document Intake

Inbound documents from fax, email, and prescriber portal captured automatically.

Automated
2

AI Classification & Routing

Vision AI classifies document type and routes to appropriate workflow with confidence scoring.

Automated
3

PA Request Creation

Structured PA request created from extracted clinical data, matched to member and prescriber.

Automated
4

Protocol Matching

Request matched to clinical protocol based on drug, diagnosis, and plan configuration.

Automated
5

Clinical AI Assessment

3-tier AI assessment: per-attachment, per-question, and holistic clinical analysis.

Automated
6

Task Population

Clinical review tasks auto-populated from protocol requirements and AI assessment results.

Automated
7
Human Touch

Clinician Review

Licensed pharmacist reviews AI assessment, clinical documents, and populated tasks.

8

ePrescribing Integration

Architected for NCPDP SCRIPT electronic prescribing with automated transaction processing.

Automated
9

SLA Monitoring

Continuous SLA tracking with escalation alerts and regulatory compliance timers.

Automated
10
Human Touch

Determination

Clinical determination made by authorized pharmacist with full audit trail.

11

Letter Generation

Determination letters auto-generated with clinical rationale and appeal instructions.

Automated
12

Audit Trail

Complete audit trail of every action, AI inference, and clinical decision.

Automated

The Human Touch

Where Humans Matter Most

7

Clinician Review

AI prepares everything — document analysis, clinical scoring, task population — but the licensed pharmacist makes the clinical judgment call. They review AI assessments with full context, validate findings against clinical documents, and apply the professional expertise that no algorithm can replace.

Why human: Clinical judgment requires professional licensure, contextual reasoning, and accountability that must rest with a qualified clinician.

10

Determination

The final approval, denial, or pend decision is made by an authorized pharmacist with a complete audit trail. Every piece of supporting evidence, every AI inference, and every clinical task result is visible at the moment of determination.

Why human: Regulatory requirement. Clinical accountability. A determination is a medical decision that carries legal weight — it must come from a licensed professional.

10

Automated Stages

2

Human Touches

12

Pipeline Stages

3

AI Assessment Tiers

"We automated everything that doesn't require clinical judgment, so pharmacists can focus entirely on the decisions that matter. The pipeline handles the paperwork; clinicians handle the medicine."

— NexusLedge Clinical Team, Clinical Operations

See the automation pipeline in action

Request a demo to see how 12 stages work end-to-end with your clinical protocols.

See the Platform